Often women in 30s but any age; 90% occur in parotid gland (represent 60% of parotid tumors; 50% occur in tail, 25% in superficial lobe, 25%. Request PDF on ResearchGate | On Mar 1, , I. Navarro and others published Adenoma pleomorfo de lóbulo profundo de parótida. Se presenta el caso clínico de un paciente masculino de 69 años de edad que consulta por un tumor (Adenoma Pleomorfo) en la región.

Author: Mozragore Samulkree
Country: Austria
Language: English (Spanish)
Genre: Literature
Published (Last): 9 June 2013
Pages: 330
PDF File Size: 8.36 Mb
ePub File Size: 16.98 Mb
ISBN: 385-5-11818-440-6
Downloads: 4745
Price: Free* [*Free Regsitration Required]
Uploader: Salmaran

It was determined as histopathological diagnosis Pleomorphic Adenoma. Embryonal rhabdomyosarcoma Sarcoma botryoides Alveolar rhabdomyosarcoma. Recurrent Pleomorphic Adenoma of the Parotid Gland. Head and Neck ; Histopathological analysis of the tumour showed a mixed epithelial and myxoid stromal appearance. The patient was reassessed at 15, 30 and 60 days after the procedure and did not show any post-operative complication Figs.

Under this description presumptive diagnosis of Pleomorphic Adenoma was made. Closure of palatal defects following excision of palatal pleomorphic adenomas. The tumor is usually solitary and presents as a slow growing, painless, firm single nodular mass.

Synovial sarcoma Clear-cell sarcoma. Benign metastasizing mixed tumors. Recent research shows that chromosomal translocations between chromosomes 3 and 8 may be responsible for tumor formation by the adenom of PLAG-1 and b-catenin gene, resulting in the activation of catenin pathway causing cell proliferation Rahnama et al.

This website is intended for pathologists and laboratory personnel, who understand that medical information is imperfect and must be interpreted using reasonable medical judgment. The epidemiology of this tumor shows that adults adenomq the most affected, with rare occurrence in children or adolescents. Histologically, it is highly variable in appearance, even within individual tumors.


Benign salivary glands tumors. The etiology of PA’s is adfnoma, however some authors mention the myoepithelial cell as responsible for the development of this pathology Ledesma-Montes et al. Patients commonly present with gradual worsening of monolateral nasal obstruction pleoomrfo occasional epistaxis.

Pleomorphic adenoma of the lateral nasal wall: case report

Nasal pleomorphic adenoma is seen predominantly in females 4 — 11 usually between the third and fifth decades of life Long term follow-up is therefore necessary for early diagnosis of loco-regional recurrences by endoscopic examination followed by imaging CT or MR in case of clinical evidence of disease. A clinicopathological study of 18 cases. The epidemiology of this neoplasm indicates that it is more common in female patients with a ratio of 2: Duct carcinoma over the pleomorphic adenoma of the parotid gland.

The intra-nasal pleomorphic adenoma shows a predominance of epithelial rather than stromal elements, as compared with major salivary gland tumours.

Pathology Outlines – Pleomorphic adenoma

The tumor is not enveloped, but it is surrounded by a fibrous pseudocapsule of varying thickness. Otolaryngol Head Neck Surg. Malignant transformation in concurrent benign mixed tumors of the parotid and submaxillary glands. Plleomorfo patient was scheduled for surgical excision of the lesion.

El carcinoma ex-tumor mixto es un adenoma pleomorfo en el que, sobre su componente epitelial, se desarrolla una neoplasia maligna. Vaciamiento cervical radical sin presencia tumoral” Figs.

Pleomorphic adenoma – Wikipedia

Enc Med Chir Orl. The endoscopic approach is preferred, as it allows complete control of the margins under direct vision and reduces the post-operative pleommorfo period when compared to open surgery.

Determinants of Survival in Parotid Gland Carcinoma: Click here for patient related inquiries. Diagnostic imaging techniques for salivary gland tumors include ultrasoundcomputer tomography CT and magnetic resonance imaging MRI. Adenome pleomorphe de la cloison nasale.

Hospital General de Ciudad Real. Pleomorphic adenoma of the palate: The tumor often displays pleomofro chromosomal translocations between chromosomes 3 and 8. Rare cases have been reported in the lip 2the hard and soft palate 3the lacrimal gland 4and the external auditory canal 5. Report of a case. It has been reported that radiotherapy as an adjuvant improves the outcome in PA’s that have been resected with inadequate margins Mendenhall et al.


None of these complications were observed in our case.

Report of a case with unusual metastatic behaviour. Conservative plelmorfo resection should be the treatment of choice to avoid recurrence or malignant transformation. Atypical features in salivary gland mixed tumors: Next it was excised down to periosteum pleomorgo a safety margin of 2 mm, complete resection of the lesion was achieved, obtaining a surgical specimen of 12 mm in diameter Fig.

Trotoux L, Lefebre B. Pleomorphic adenoma Warthin’s tumor. Various theories have been proposed to explain this observation. Brenner tumour Fibroadenoma Phyllodes tumor. Not as well circumscribed as may grossly appear, with tongue like protrusions into surrounding salivary gland Pleoomrfo capsule if present in deep parotid lobe Biphasic population of epithelial and mesenchymal cells Epithelial cells are glandular or occasionally squamous; may be spindled or oval, have large hyperchromatic nuclei Myoepithelial basal layer or overlying pseudoepitheliomatous hyperplasia; tumor may be very cellular Stroma is myxoid, hyaline, chondroid, rarely adipose tissue or osseous; mucin often present Occasional angiolymphatic invasion May have adenoid cystic pattern No mitotic figures, no necrosis.

Author: admin